I have run them on my EXC450 for a bit over a year now and have mixed thoughts about them.
They do all the things they clame run cooler, less wieght, run lower pressure ect but I would have had more flat tyres running them than I did have running extra heavy duty tubes.
I had flats
from the rimlock holing the tyre, failure of the high pressure tube, and the last flat was failure of the red liner (Tubliss sent me a new system after I emailed them with pics).
I now carry with me a front & rear highpressure tubes, slime, high pressure canisterters (to get enough pressure into the high pressure tube, plugs & a rimlock in case I have another failure so I can put a normal tube back in to get me home which is more gear than carrying a spare tube.
If I get any more problems with flat tyres from the tubliss system I will be going back to heavy duty tubes.
I now also have a Tenere which I will run heavy tubes.